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Rhodium‐Catalyzed Cyclization of Terminal and Internal Allenols: An Atom Economic and Highly Stereoselective Access Towards Tetrahydropyrans

A comprehensive study of a diastereoselective Rh‐catalyzed cyclization of terminal and internal allenols is reported. The methodology allows the atom economic and highly syn‐selective access to synthetically important 2,4‐disubstituted and 2,4,6‐trisubstituted tetrahydropyrans (THP). Furthermore, it...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Schmidt, Johannes P., Breit, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756761/
https://ncbi.nlm.nih.gov/pubmed/32940396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202009166
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