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A rhodium catalyzed cycloisomerization and tandem Diels–Alder reaction for facile access to diverse bicyclic and tricyclic heterocycles

A regioselective distal cycloisomerization of 1,6-allenenes was successfully developed to afford six-membered ring exocyclic 1,3-dienes employing a rhodium/diphosphine catalyst system. Deuterium labelling experiments and DFT calculations were performed to provide insights into the reaction mechanism...

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Publicat a:Chem Sci
Autors principals: Zhou, Yirong, Nikbakht, Ali, Bauer, Felix, Breit, Bernhard
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521805/
https://ncbi.nlm.nih.gov/pubmed/31183033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00980a
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