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Features of increased malignancy in eosinophilic clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common form of renal cancer. Due to inactivation of the von Hippel–Lindau tumour suppressor, the hypoxia‐inducible transcription factors (HIFs) are constitutively activated in these tumours, resulting in a pseudo‐hypoxic phenotype. The HIFs induce...

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Publicat a:J Pathol
Autors principals: Nilsson, Helén, Lindgren, David, Axelson, Håkan, Brueffer, Christian, Saal, Lao H, Lundgren, Jaana, Johansson, Martin E
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756750/
https://ncbi.nlm.nih.gov/pubmed/32815150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5532
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