Features of increased malignancy in eosinophilic clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common form of renal cancer. Due to inactivation of the von Hippel–Lindau tumour suppressor, the hypoxia‐inducible transcription factors (HIFs) are constitutively activated in these tumours, resulting in a pseudo‐hypoxic phenotype. The HIFs induce...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Nilsson, Helén, Lindgren, David, Axelson, Håkan, Brueffer, Christian, Saal, Lao H, Lundgren, Jaana, Johansson, Martin E
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2020
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756750/
https://ncbi.nlm.nih.gov/pubmed/32815150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5532
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