Features of increased malignancy in eosinophilic clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common form of renal cancer. Due to inactivation of the von Hippel–Lindau tumour suppressor, the hypoxia‐inducible transcription factors (HIFs) are constitutively activated in these tumours, resulting in a pseudo‐hypoxic phenotype. The HIFs induce...

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Bibliographic Details
Published in:J Pathol
Main Authors: Nilsson, Helén, Lindgren, David, Axelson, Håkan, Brueffer, Christian, Saal, Lao H, Lundgren, Jaana, Johansson, Martin E
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2020
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756750/
https://ncbi.nlm.nih.gov/pubmed/32815150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5532
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