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Non-full-length Water-Soluble CXCR4(QTY) and CCR5(QTY) Chemokine Receptors: Implication for Overlooked Truncated but Functional Membrane Receptors
It was posited that functionalities of GPCRs require full-length sequences that are negated by residue deletions. Here we report that significantly truncated nfCCR5(QTY) and nfCXCR4(QTY) still bind native ligands. Receptor-ligand interactions were discovered from yeast 2-hybrid screening and confirm...
সংরক্ষণ করুন:
| প্রকাশিত: | iScience |
|---|---|
| প্রধান লেখক: | , , , , , , , , , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Elsevier
2020
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7756140/ https://ncbi.nlm.nih.gov/pubmed/33376963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101670 |
| ট্যাগগুলো: |
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