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QTY code designed thermostable and water-soluble chimeric chemokine receptors with tunable ligand affinity

Chemokine receptors are of great interest as they play a critical role in many immunological and pathological processes. The ability to study chemokine receptors in aqueous solution without detergent would be significant because natural receptors require detergents to become soluble. We previously r...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Qing, Rui, Han, Qiuyi, Skuhersky, Michael, Chung, Haeyoon, Badr, Myriam, Schubert, Thomas, Zhang, Shuguang
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926000/
https://ncbi.nlm.nih.gov/pubmed/31776256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909026116
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