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QTY code designed thermostable and water-soluble chimeric chemokine receptors with tunable ligand affinity

Chemokine receptors are of great interest as they play a critical role in many immunological and pathological processes. The ability to study chemokine receptors in aqueous solution without detergent would be significant because natural receptors require detergents to become soluble. We previously r...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Qing, Rui, Han, Qiuyi, Skuhersky, Michael, Chung, Haeyoon, Badr, Myriam, Schubert, Thomas, Zhang, Shuguang
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926000/
https://ncbi.nlm.nih.gov/pubmed/31776256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909026116
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