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QTY code designed thermostable and water-soluble chimeric chemokine receptors with tunable ligand affinity

Chemokine receptors are of great interest as they play a critical role in many immunological and pathological processes. The ability to study chemokine receptors in aqueous solution without detergent would be significant because natural receptors require detergents to become soluble. We previously r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Qing, Rui, Han, Qiuyi, Skuhersky, Michael, Chung, Haeyoon, Badr, Myriam, Schubert, Thomas, Zhang, Shuguang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926000/
https://ncbi.nlm.nih.gov/pubmed/31776256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909026116
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