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Niraparib as Maintenance Therapy in Germline ATM-mutated and Somatic BRCA2-mutated Ovarian Cancer with Brain Metastases: A Case Report and Literature Review

Brain metastases from epithelial ovarian cancer are very rare with an incidence of only 1–2.5%. Many therapeutic methods such as surgery, irradiation and chemotherapy do produce survival benefits, but the overall outcome remains unsatisfactory. The BRCA (breast cancer susceptibility gene) mutation s...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Tao, Mengyu, Cheng, Jiejun, Wu, Xia
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755878/
https://ncbi.nlm.nih.gov/pubmed/33376347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S281302
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