Prevalence and clinical significance of BRCA1/2 germline and somatic mutations in Taiwanese patients with ovarian cancer

Germline and somatic BRCA1/2 mutations define a subset of patients with ovarian cancer who may benefit from treatment with poly (ADP-ribose) polymerase inhibitors. Unfortunately, data on the frequency of BRCA1/2 germline mutations in Taiwanese patients with ovarian cancer are scarce, with the preval...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chao, Angel, Chang, Ting-Chang, Lapke, Nina, Jung, Shih-Ming, Chi, Peter, Chen, Chien-Hung, Yang, Lan-Yan, Lin, Cheng-Tao, Huang, Huei-Jean, Chou, Hung-Hsueh, Liou, Jui-Der, Chen, Shu-Jen, Wang, Tzu-Hao, Lai, Chyong-Huey
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356755/
https://ncbi.nlm.nih.gov/pubmed/27907908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13456
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