Patterns of germline and somatic mutations in 16 genes associated with mismatch repair function or containing tandem repeat sequences

BACKGROUND: We assumed that targeted next‐generation sequencing (NGS) of mismatch repair‐associated genes could improve the detection of driving mutations in colorectal cancers (CRC) with microsatellite instability (MSI) and microsatellite alterations at selected tetranucleotide repeats (EMAST) and...

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Veröffentlicht in:Cancer Med
Hauptverfasser: Chang, Shih‐Ching, Lan, Yuan‐Tzu, Lin, Pei‐Ching, Yang, Shung‐Haur, Lin, Chien‐Hsing, Liang, Wen‐Yi, Chen, Wei‐Shone, Jiang, Jeng‐Kai, Lin, Jen‐Kou
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Clinical Cancer Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970039/
https://ncbi.nlm.nih.gov/pubmed/31769227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2702
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