Patterns of germline and somatic mutations in 16 genes associated with mismatch repair function or containing tandem repeat sequences

BACKGROUND: We assumed that targeted next‐generation sequencing (NGS) of mismatch repair‐associated genes could improve the detection of driving mutations in colorectal cancers (CRC) with microsatellite instability (MSI) and microsatellite alterations at selected tetranucleotide repeats (EMAST) and...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Chang, Shih‐Ching, Lan, Yuan‐Tzu, Lin, Pei‐Ching, Yang, Shung‐Haur, Lin, Chien‐Hsing, Liang, Wen‐Yi, Chen, Wei‐Shone, Jiang, Jeng‐Kai, Lin, Jen‐Kou
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970039/
https://ncbi.nlm.nih.gov/pubmed/31769227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2702
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