Patterns of germline and somatic mutations in 16 genes associated with mismatch repair function or containing tandem repeat sequences

BACKGROUND: We assumed that targeted next‐generation sequencing (NGS) of mismatch repair‐associated genes could improve the detection of driving mutations in colorectal cancers (CRC) with microsatellite instability (MSI) and microsatellite alterations at selected tetranucleotide repeats (EMAST) and...

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Vydáno v:Cancer Med
Hlavní autoři: Chang, Shih‐Ching, Lan, Yuan‐Tzu, Lin, Pei‐Ching, Yang, Shung‐Haur, Lin, Chien‐Hsing, Liang, Wen‐Yi, Chen, Wei‐Shone, Jiang, Jeng‐Kai, Lin, Jen‐Kou
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Clinical Cancer Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970039/
https://ncbi.nlm.nih.gov/pubmed/31769227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2702
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