Patterns of germline and somatic mutations in 16 genes associated with mismatch repair function or containing tandem repeat sequences

Abstract Background We assumed that targeted next‐generation sequencing (NGS) of mismatch repair‐associated genes could improve the detection of driving mutations in colorectal cancers (CRC) with microsatellite instability (MSI) and microsatellite alterations at selected tetranucleotide repeats (EMA...

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Detalhes bibliográficos

Principais autores:	Shih‐Ching Chang, Yuan‐Tzu Lan, Pei‐Ching Lin, Shung‐Haur Yang, Chien‐Hsing Lin, Wen‐Yi Liang, Wei‐Shone Chen, Jeng‐Kai Jiang, Jen‐Kou Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2020-01-01
coleção:	Cancer Medicine
Assuntos:	colorectal cancer EMAST MMR MSI mutation
Acesso em linha:	https://doi.org/10.1002/cam4.2702
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