Elevated In Vitro Kinase Activity in Peripheral Blood Mononuclear Cells of Leucine‐Rich Repeat Kinase 2 G2019S Carriers: A Novel Enzyme‐Linked Immunosorbent Assay–Based Method

BACKGROUND: Leucine‐rich repeat kinase 2 kinase inhibitors are being vigorously pursued as potential therapeutic options; however, there is a critical need for sensitive and quantitative assays of leucine‐rich repeat kinase 2 function and target engagement. OBJECTIVES: Our objective was to compare c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mov Disord
Egile Nagusiak: Melachroinou, Katerina, Kang, Min Suk, Liong, Christopher, Narayan, Sushma, Levers, Najah, Joshi, Neal, Kopil, Katie, Hutten, Samantha J., Baptista, Marco A.S., Padmanabhan, Shalini, Kang, Un Jung, Stefanis, Leonidas, Alcalay, Roy N., Rideout, Hardy J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Inc. 2020
Gaiak:
Regular Issue Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754308/
https://ncbi.nlm.nih.gov/pubmed/32652692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.28175
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