Analysis of Complex DNA Rearrangements during Early Stages of HAC Formation

[Image: see text] Human artificial chromosomes (HACs) are important tools for epigenetic engineering, for measuring chromosome instability (CIN), and for possible gene therapy. However, their use in the latter is potentially limited because the input HAC-seeding DNA can undergo an unpredictable seri...

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Dades bibliogràfiques
Publicat a:ACS Synth Biol
Autors principals: Pesenti, Elisa, Liskovykh, Mikhail, Okazaki, Koei, Mallozzi, Alessio, Reid, Caitlin, Abad, Maria Alba, Jeyaprakash, A. Arockia, Kouprina, Natalay, Larionov, Vladimir, Masumoto, Hiroshi, Earnshaw, William C.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754191/
https://ncbi.nlm.nih.gov/pubmed/33289546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.0c00326
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