Analysis of Complex DNA Rearrangements during Early Stages of HAC Formation

[Image: see text] Human artificial chromosomes (HACs) are important tools for epigenetic engineering, for measuring chromosome instability (CIN), and for possible gene therapy. However, their use in the latter is potentially limited because the input HAC-seeding DNA can undergo an unpredictable seri...

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發表在:ACS Synth Biol
Main Authors: Pesenti, Elisa, Liskovykh, Mikhail, Okazaki, Koei, Mallozzi, Alessio, Reid, Caitlin, Abad, Maria Alba, Jeyaprakash, A. Arockia, Kouprina, Natalay, Larionov, Vladimir, Masumoto, Hiroshi, Earnshaw, William C.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2020
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754191/
https://ncbi.nlm.nih.gov/pubmed/33289546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.0c00326
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