Disruption of microRNA‐214 during general anaesthesia prevents brain injury and maintains mitochondrial fusion by promoting Mfn2 interaction with Pkm2

Duration of surgical general anaesthesia is associated with severe brain injury and neurological deficits. The specific mechanisms underlying post‐general anaesthesia brain injury, however, still remain to be elucidated. Herein, we explore the role of microRNA‐214 (miR‐214) in the occurrence of brai...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Liu, Tiejun, Wang, Bin, Li, Gai, Dong, Xiaoliu, Yu, Guannan, Qian, Qingzeng, Duan, Likun, Li, Hongxia, Jia, Zhao, Bai, Jing
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753869/
https://ncbi.nlm.nih.gov/pubmed/33147380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15222
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