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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

Mitochondrial morphology is determined by a dynamic equilibrium between organelle fusion and fission, but the significance of these processes in vertebrates is unknown. The mitofusins, Mfn1 and Mfn2, have been shown to affect mitochondrial morphology when overexpressed. We find that mice deficient i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Hsiuchen, Detmer, Scott A., Ewald, Andrew J., Griffin, Erik E., Fraser, Scott E., Chan, David C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172648/
https://ncbi.nlm.nih.gov/pubmed/12527753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200211046
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