Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

Mitochondria are dynamic organelles that play a key role in energy conversion. Optimal mitochondrial function is ensured by a quality-control system tightly coupled to fusion and fission. In this connection, mitofusin 2 (Mfn2) participates in mitochondrial fusion and undergoes repression in muscle f...

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Détails bibliographiques
Auteurs principaux: Sebastián, David, Hernández-Alvarez, María Isabel, Segalés, Jessica, Sorianello, Eleonora, Muñoz, Juan Pablo, Sala, David, Waget, Aurélie, Liesa, Marc, Paz, José C., Gopalacharyulu, Peddinti, Orešič, Matej, Pich, Sara, Burcelin, Rémy, Palacín, Manuel, Zorzano, Antonio
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325712/
https://ncbi.nlm.nih.gov/pubmed/22427360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108220109
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