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MiR-106b-mediated Mfn2 suppression is critical for PKM2 induced mitochondrial fusion
Cancer cells preferentially metabolize glucose through aerobic glycolysis. This phenomenon, known as the Warburg effect, is a characteristic of glucose metabolism in cancer cells. PKM2 is reported to imply an important role in glycolysis. However, whether and how PKM2 can cause mitochondrial dysfunc...
Uloženo v:
| Vydáno v: | Am J Cancer Res |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
e-Century Publishing Corporation
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5088287/ https://ncbi.nlm.nih.gov/pubmed/27822413 |
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