RNF20 Is Critical for Snail-Mediated E-Cadherin Repression in Human Breast Cancer

BACKGROUND: E-cadherin, a hallmark of epithelial-mesenchymal transition (EMT), is often repressed due to Snail-mediated epigenetic modification; however, the exact mechanism remains unclear. There is an urgent need to understand the determinants of tumor aggressiveness and identify potential therape...

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Vydáno v:Front Oncol
Hlavní autoři: Wang, Danping, Wang, Yifan, Wu, Xuebiao, Kong, Xiangxing, Li, Jun, Dong, Chenfang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753216/
https://ncbi.nlm.nih.gov/pubmed/33364200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.613470
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