G9a and histone deacetylases are crucial for Snail2‐mediated E‐cadherin repression and metastasis in hepatocellular carcinoma

Functional E‐cadherin loss, a hallmark of epithelial‐mesenchymal transition (EMT), is important for metastasis. However, the mechanism of Snail2 in hepatocellular carcinoma (HCC) EMT and metastasis remains unclear. Here, we showed that Snail2 was upregulated in primary HCC, and significantly increas...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Hu, Yue, Zheng, Yayuan, Dai, Mingrui, Wang, Xueju, Wu, Jiaxin, Yu, Bin, Zhang, Haihong, Cui, Yinqiu, Kong, Wei, Wu, Hui, Yu, Xianghui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825017/
https://ncbi.nlm.nih.gov/pubmed/31432592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14173
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