Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs

Snail2 is a repressor of E-cadherin during carcinogenesis; however, the specific mechanisms involved in this process remain largely unknown. Here, we determined that Snail2 was highly increased during TGF-β-induced EMT process in lung cells. H3K9 methylation was up-regulated and H3K4/H3K56 acetylati...

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Bibliografiske detaljer
Udgivet i:Cell Adh Migr
Main Authors: Hu, Yue, Zheng, Yayuan, Dai, Mingrui, Wu, Jiaxin, Yu, Bin, Zhang, Haihong, Kong, Wei, Wu, Hui, Yu, Xianghui
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629185/
https://ncbi.nlm.nih.gov/pubmed/31271097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2019.1638689
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