Loss of FBP1 by Snail-mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer

Epithelial-mesenchymal transition (EMT) enhances invasiveness and confers tumor cells with cancer stem cell (CSC)-like characteristics. We showed that the Snail-G9a-Dnmt1 complex, which is critical for E-cadherin promoter silencing, is also required for the promoter methylation of fructose-1,6-bipho...

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Autori principali: Dong, Chenfang, Yuan, Tingting, Wu, Yadi, Wang, Yifan, Fan, Teresa W.M., Miriyala, Sumitra, Lin, Yiwei, Yao, Jun, Shi, Jian, Kang, Tiebang, Lorkiewicz, Pawel, St Clair, Daret, Hung, Mien-Chie, Evers, B. Mark, Zhou, Binhua P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703516/
https://ncbi.nlm.nih.gov/pubmed/23453623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.01.022
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