The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1

Epithelial–mesenchymal transition (EMT) is a transdifferentiation programme. The mechanism underlying the epigenetic regulation of EMT remains unclear. In this study, we identified that Snail1 interacted with histone lysine-specific demethylase 1 (LSD1). We demonstrated that the SNAG domain of Snail...

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Autors principals: Lin, Yiwei, Wu, Yadi, Li, Junlin, Dong, Chenfang, Ye, Xiaofeng, Chi, Young-In, Evers, B Mark, Zhou, Binhua P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885925/
https://ncbi.nlm.nih.gov/pubmed/20389281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.63
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