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Small C-terminal Domain Phosphatase Enhances Snail Activity through Dephosphorylation

Down-regulation of E-cadherin plays an important role in epithelial-mesenchymal transition (EMT), which is critical in normal development and disease states such as tissue fibrosis and metastasis. Snail, a key transcription repressor of E-cadherin, is a labile protein with a short half-life and is r...

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Hlavní autoři: Wu, Yadi, Evers, B. Mark, Zhou, Binhua P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610500/
https://ncbi.nlm.nih.gov/pubmed/19004823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806916200
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