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Small C-terminal Domain Phosphatase Enhances Snail Activity through Dephosphorylation
Down-regulation of E-cadherin plays an important role in epithelial-mesenchymal transition (EMT), which is critical in normal development and disease states such as tissue fibrosis and metastasis. Snail, a key transcription repressor of E-cadherin, is a labile protein with a short half-life and is r...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2610500/ https://ncbi.nlm.nih.gov/pubmed/19004823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806916200 |
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