C-terminal Domain (CTD) Small Phosphatase-like 2 Modulates the Canonical Bone Morphogenetic Protein (BMP) Signaling and Mesenchymal Differentiation via Smad Dephosphorylation

The bone morphogenetic protein (BMP) signaling pathway regulates a wide range of cellular responses in metazoans. A key step in the canonical BMP signaling is the phosphorylation and activation of transcription factors Smad1, Smad5, and Smad8 (collectively Smad1/5/8) by the type I BMP receptors. We...

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Hlavní autoři: Zhao, Yulan, Xiao, Mu, Sun, Baoguo, Zhang, Zhengmao, Shen, Tao, Duan, Xueyan, Yu, Paul Borchyung, Feng, Xin-Hua, Lin, Xia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176200/
https://ncbi.nlm.nih.gov/pubmed/25100727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568964
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