Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR

MOTIVATION: Determining the relative contributions of functional genetic categories is fundamental to understanding the genetic etiology of complex human traits and diseases. Here, we present Annotation Informed-MiXeR, a likelihood-based method for estimating the number of variants influencing a phe...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Bioinformatics
Asıl Yazarlar: Shadrin, Alexey A, Frei, Oleksandr, Smeland, Olav B, Bettella, Francesco, O'Connell, Kevin S, Gani, Osman, Bahrami, Shahram, Uggen, Tea K E, Djurovic, Srdjan, Holland, Dominic, Andreassen, Ole A, Dale, Anders M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Original Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750998/
https://ncbi.nlm.nih.gov/pubmed/32539089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa568
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller