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Development of a sequencing system for spatial decoding of DNA barcode molecules at single-molecule resolution

Single-cell transcriptome analysis has been revolutionized by DNA barcodes that index cDNA libraries, allowing highly multiplexed analyses to be performed. Furthermore, DNA barcodes are being leveraged for spatial transcriptomes. Although spatial resolution relies on methods used to decode DNA barco...

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Foilsithe in:Commun Biol
Main Authors: Oguchi, Yusuke, Shintaku, Hirofumi, Uemura, Sotaro
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749132/
https://ncbi.nlm.nih.gov/pubmed/33339962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01499-8
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