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Droplet barcoding for massively parallel single-molecule deep sequencing

The ability to accurately sequence long DNA molecules is important across biology, but existing sequencers are limited in read length and accuracy. Here, we demonstrate a method to leverage short-read sequencing to obtain long and accurate reads. Using droplet microfluidics, we isolate, amplify, fra...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Lan, Freeman, Haliburton, John R., Yuan, Aaron, Abate, Adam R.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931254/
https://ncbi.nlm.nih.gov/pubmed/27353563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11784
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