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Phasing of single DNA molecules by massively parallel barcoding

High-throughput sequencing platforms mainly produce short-read data, resulting in a loss of phasing information for many of the genetic variants analysed. For certain applications, it is vital to know which variant alleles are connected to each individual DNA molecule. Here we demonstrate a method f...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Borgström, Erik, Redin, David, Lundin, Sverker, Berglund, Emelie, Andersson, Anders F., Ahmadian, Afshin
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468844/
https://ncbi.nlm.nih.gov/pubmed/26055759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8173
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