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Phasing of single DNA molecules by massively parallel barcoding

High-throughput sequencing platforms mainly produce short-read data, resulting in a loss of phasing information for many of the genetic variants analysed. For certain applications, it is vital to know which variant alleles are connected to each individual DNA molecule. Here we demonstrate a method f...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Borgström, Erik, Redin, David, Lundin, Sverker, Berglund, Emelie, Andersson, Anders F., Ahmadian, Afshin
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468844/
https://ncbi.nlm.nih.gov/pubmed/26055759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8173
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