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Phasing of single DNA molecules by massively parallel barcoding

High-throughput sequencing platforms mainly produce short-read data, resulting in a loss of phasing information for many of the genetic variants analysed. For certain applications, it is vital to know which variant alleles are connected to each individual DNA molecule. Here we demonstrate a method f...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Borgström, Erik, Redin, David, Lundin, Sverker, Berglund, Emelie, Andersson, Anders F., Ahmadian, Afshin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468844/
https://ncbi.nlm.nih.gov/pubmed/26055759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8173
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