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Multiplex single-molecule interaction profiling of DNA barcoded proteins

In contrast with advances in massively parallel DNA sequencing(1), high-throughput protein analyses(2-4) are often limited by ensemble measurements, individual analyte purification and hence compromised quality and cost-effectiveness. Single-molecule (SM) protein detection achieved using optical met...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Gu, Liangcai, Li, Chao, Aach, John, Hill, David E., Vidal, Marc, Church, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246050/
https://ncbi.nlm.nih.gov/pubmed/25252978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13761
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