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Predictive Analysis of the Side Chain Conformation of the Higher Carbon Sugars: Application to the Preorganization of the Aminoglycoside Ring 1 Side Chain for Binding to the Bacterial Ribosomal Decoding A Site
With a view to facilitating prediction of the exocyclic bond to the pyranoside ring in higher carbon sugars a model is advanced that relates the relative configuration of the three stereogenic centers comprised of the branchpoint and of the two flanking centers (C4–C5–C6 in aldoheptoses and higher,...
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| Pubblicato in: | J Org Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749010/ https://ncbi.nlm.nih.gov/pubmed/32902280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c01836 |
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