Mycolactone toxin induces an inflammatory response by targeting the IL-1β pathway: Mechanistic insight into Buruli ulcer pathophysiology

Mycolactone, a lipid-like toxin, is the major virulence factor of Mycobacterium ulcerans, the etiological agent of Buruli ulcer. Its involvement in lesion development has been widely described in early stages of the disease, through its cytotoxic and immunosuppressive activities, but less is known a...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Foulon, M., Robbe-Saule, M., Manry, J., Esnault, L., Boucaud, Y., Alcaïs, A., Malloci, M., Fanton d’Andon, M., Beauvais, T., Labarriere, N., Jeannin, P., Abel, L., Saint-André, J. P., Croué, A., Delneste, Y., Boneca, I. G., Marsollier, L., Marion, E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748131/
https://ncbi.nlm.nih.gov/pubmed/33338061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009107
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