Mycolactone Diffuses into the Peripheral Blood of Buruli Ulcer Patients - Implications for Diagnosis and Disease Monitoring

BACKGROUND: Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU), is unique among human pathogens in its capacity to produce a polyketide-derived macrolide called mycolactone, making this molecule an attractive candidate target for diagnosis and disease monitoring. Whether mycolactone di...

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Detalhes bibliográficos
Main Authors: Sarfo, Fred S., Le Chevalier, Fabien, Aka, N'Guetta, Phillips, Richard O., Amoako, Yaw, Boneca, Ivo G., Lenormand, Pascal, Dosso, Mireille, Wansbrough-Jones, Mark, Veyron-Churlet, Romain, Guenin-Macé, Laure, Demangel, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139662/
https://ncbi.nlm.nih.gov/pubmed/21811642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001237
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