Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system

Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU) disease, is unique amongst human pathogens in its capacity to produce a lipid toxin called mycolactone. While previous studies have demonstrated that bacterially-released mycolactone diffuses beyond infection foci, the spatiotemporal d...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Colucci-Guyon, Emma, Rifflet, Aline, Saint-Auret, Sarah, da Costa, Anaëlle, Boucontet, Laurent, Laval, Thomas, Prehaud, Christophe, Blanchard, Nicolas, Levraud, Jean-Pierre, Boneca, Ivo G., Demangel, Caroline, Guenin-Macé, Laure
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710047/
https://ncbi.nlm.nih.gov/pubmed/33264290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008878
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