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Mycolactone displays anti-inflammatory effects on the nervous system
BACKGROUND: Mycolactone is a macrolide produced by the skin pathogen Mycobacterium ulcerans, with cytotoxic, analgesic and immunomodulatory properties. The latter were recently shown to result from mycolactone blocking the Sec61-dependent production of pro-inflammatory mediators by immune cells. Her...
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| Publicado no: | PLoS Negl Trop Dis |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693295/ https://ncbi.nlm.nih.gov/pubmed/29149212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006058 |
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