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Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

[Image: see text] Antibodies are attractive as radioligands due to their outstanding specificity and high affinity, but their inability to cross the blood–brain barrier (BBB) limits their use for CNS targets. To enhance brain distribution, amyloid-β (Aβ) antibodies were fused to a transferrin recept...

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書目詳細資料
發表在:ACS Chem Neurosci
Main Authors: Syvänen, Stina, Fang, Xiaotian T, Faresjö, Rebecca, Rokka, Johanna, Lannfelt, Lars, Olberg, Dag E, Eriksson, Jonas, Sehlin, Dag
格式: Artigo
語言:Inglês
出版: American Chemical Society 2020
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747219/
https://ncbi.nlm.nih.gov/pubmed/33236886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00652
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