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Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain
[Image: see text] Antibodies are attractive as radioligands due to their outstanding specificity and high affinity, but their inability to cross the blood–brain barrier (BBB) limits their use for CNS targets. To enhance brain distribution, amyloid-β (Aβ) antibodies were fused to a transferrin recept...
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| Publicado no: | ACS Chem Neurosci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7747219/ https://ncbi.nlm.nih.gov/pubmed/33236886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00652 |
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