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Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease

Owing to their specificity and high-affinity binding, monoclonal antibodies have potential as positron emission tomography (PET) radioligands and are currently used to image various targets in peripheral organs. However, in the central nervous system, antibody uptake is limited by the blood–brain ba...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Sehlin, Dag, Fang, Xiaotian T., Cato, Linda, Antoni, Gunnar, Lannfelt, Lars, Syvänen, Stina
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762893/
https://ncbi.nlm.nih.gov/pubmed/26892305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10759
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