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Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease
Owing to their specificity and high-affinity binding, monoclonal antibodies have potential as positron emission tomography (PET) radioligands and are currently used to image various targets in peripheral organs. However, in the central nervous system, antibody uptake is limited by the blood–brain ba...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4762893/ https://ncbi.nlm.nih.gov/pubmed/26892305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10759 |
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