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Interfacial inhibitors
Targeting macromolecular interface is a general mechanism by which natural products inactivate macromolecular complexes by stabilizing normally transient intermediates. Demonstrating interfacial inhibition mechanism ultimately relies on the resolution of drug-macromolecule structures. This review fo...
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| Pubblicato in: | Bioorg Med Chem Lett |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7747010/ https://ncbi.nlm.nih.gov/pubmed/26235949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.07.032 |
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