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Interfacial inhibitors: targeting macromolecular complexes
Interfacial inhibitors belong to a broad class of natural products and synthetic drugs that are commonly used to treat cancers as well as bacterial and HIV infections. They bind selectively to interfaces as macromolecular machines assemble and are set in motion. The bound drugs transiently arrest th...
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| Udgivet i: | Nat Rev Drug Discov |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380715/ https://ncbi.nlm.nih.gov/pubmed/22173432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3404 |
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