Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with human papillomavirus-associated malignancies

BACKGROUND: Bintrafusp alfa is a first-in-class bifunctional fusion protein composed of the extracellular domain of transforming growth factor (TGF)-βRII (a TGF-β ‘trap’) fused to a human IgG1 mAb blocking programmed cell death ligand 1. This is the largest analysis of patients with advanced, pretre...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Immunother Cancer
Main Authors: Strauss, Julius, Gatti-Mays, Margaret E, Cho, Byoung Chul, Hill, Andrew, Salas, Sébastien, McClay, Edward, Redman, Jason M, Sater, Houssein A, Donahue, Renee N, Jochems, Caroline, Lamping, Elizabeth, Burmeister, Andrea, Marté, Jennifer L, Cordes, Lisa M, Bilusic, Marijo, Karzai, Fatima, Ojalvo, Laureen S, Jehl, Genevieve, Rolfe, P Alexander, Hinrichs, Christian S, Madan, Ravi A, Schlom, Jeffrey, Gulley, James L
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2020
Fag:
Clinical/Translational Cancer Immunotherapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7745517/
https://ncbi.nlm.nih.gov/pubmed/33323462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001395
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker