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The Role of Orthosteric Building Blocks of Bitopic Ligands for Muscarinic M1 Receptors
[Image: see text] The muscarinic M(1) acetylcholine receptor is an important drug target for the treatment of various neurological disorders. Designing M(1) receptor-selective drugs has proven challenging, mainly due to the high conservation of the acetylcholine binding site among muscarinic recepto...
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| Опубликовано в: : | ACS Omega |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical Society
2020
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745449/ https://ncbi.nlm.nih.gov/pubmed/33344823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c04220 |
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