Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling

[Image: see text] Allosteric coupling describes a reciprocal process whereby G-protein-coupled receptors (GPCRs) relay ligand-induced conformational changes from the extracellular binding pocket to the intracellular signaling surface. Therefore, GPCR activation is sensitive to both the type of extra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Holze, Janine, Bermudez, Marcel, Pfeil, Eva Marie, Kauk, Michael, Bödefeld, Theresa, Irmen, Matthias, Matera, Carlo, Dallanoce, Clelia, De Amici, Marco, Holzgrabe, Ulrike, König, Gabriele Maria, Tränkle, Christian, Wolber, Gerhard, Schrage, Ramona, Mohr, Klaus, Hoffmann, Carsten, Kostenis, Evi, Bock, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551708/
https://ncbi.nlm.nih.gov/pubmed/33073186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00069
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados