Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling

[Image: see text] Allosteric coupling describes a reciprocal process whereby G-protein-coupled receptors (GPCRs) relay ligand-induced conformational changes from the extracellular binding pocket to the intracellular signaling surface. Therefore, GPCR activation is sensitive to both the type of extra...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:ACS Pharmacol Transl Sci
Huvudupphovsmän: Holze, Janine, Bermudez, Marcel, Pfeil, Eva Marie, Kauk, Michael, Bödefeld, Theresa, Irmen, Matthias, Matera, Carlo, Dallanoce, Clelia, De Amici, Marco, Holzgrabe, Ulrike, König, Gabriele Maria, Tränkle, Christian, Wolber, Gerhard, Schrage, Ramona, Mohr, Klaus, Hoffmann, Carsten, Kostenis, Evi, Bock, Andreas
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2020
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551708/
https://ncbi.nlm.nih.gov/pubmed/33073186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00069
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk