Clinical Evolution of AmpC-Mediated Ceftazidime-Avibactam and Cefiderocol Resistance in Enterobacter cloacae Complex Following Exposure to Cefepime

We report 2 independent patients from whom carbapenem and ceftazidime-avibactam–resistant Enterobacter cloacae complex strains were identified. The ceftazidime-avibactam resistance was attributed to a 2–amino acid deletion in the R2 loop of AmpC β-lactamase, which concurrently caused resistance to c...

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Bibliographic Details
Published in:Clin Infect Dis
Main Authors: Shields, Ryan K, Iovleva, Alina, Kline, Ellen G, Kawai, Akito, McElheny, Christi L, Doi, Yohei
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744991/
https://ncbi.nlm.nih.gov/pubmed/32236408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciaa355
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