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26. in Vitro selection Of enterobacter Cloacae with Cefepime, Meropenem, and Ceftazidime-avibactam Generate Diverse Resistance Mechanism

BACKGROUND: Acquired β-lactamases are not a common β-lactam resistance mechanism in E. cloacae. In this species, porin mutations decreasing β-lactams permeability are associated with overexpression of the constitutive AmpC with or without increased efflux contributing to β-lactam resistance. We subj...

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Bibliografiske detaljer
Udgivet i:Open Forum Infect Dis
Main Authors: Castanheira, Mariana, Lindley, Jill, Roth, Brieanna, Doyle, Timothy B, Davis, Andrew P, Sader, Helio S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7776091/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofaa417.025
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