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Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence
Chronic inflammation promotes prostate cancer (PCa) initiation and progression. We previously reported that acute intereluekin-1 (IL-1) exposure represses androgen receptor (AR) accumulation and activity, providing a possible mechanism for IL-1-mediated development of androgen- and AR-independent PC...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7743957/ https://ncbi.nlm.nih.gov/pubmed/33326447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242970 |
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