Identification of an IL-1-induced gene expression pattern in AR(+) PCa cells that mimics the molecular phenotype of AR(−) PCa cells

Por Thomas-Jardin, Shayna E., Kanchwala, Mohammed S., Jacob, Joan, Merchant, Sana, Meade, Rachel K., Gahnim, Nagham M., Nawas, Afshan F., Xing, Chao, Delk, Nikki A.
Publicado no Prostate (2018)

Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence

Por Dahl, Haley C., Kanchwala, Mohammed, Thomas-Jardin, Shayna E., Sandhu, Amrit, Kanumuri, Preethi, Nawas, Afshan F., Xing, Chao, Lin, Chenchu, Frigo, Daniel E., Delk, Nikki A.
Publicado no PLoS One (2020)

RELA is sufficient to mediate interleukin-1 repression of androgen receptor expression and activity in an LNCaP disease progression model

Por Thomas-Jardin, Shayna E., Dahl, Haley, Kanchwala, Mohammed S., Ha, Freedom, Jacob, Joan, Soundharrajan, Reshma, Bautista, Monica, Nawas, Afshan F., Robichaux, Dexter, Mistry, Ragini, Anunobi, Vanessa, Xing, Chao, Delk, Nikki A.
Publicado no Prostate (2019)

IL-1-conferred gene expression pattern in ERα(+) BCa and AR(+) PCa cells is intrinsic to ERα(−) BCa and AR(−) PCa cells and promotes cell survival

Por Nawas, Afshan F., Kanchwala, Mohammed, Thomas-Jardin, Shayna E., Dahl, Haley, Daescu, Kelly, Bautista, Monica, Anunobi, Vanessa, Wong, Ally, Meade, Rachel, Mistry, Ragini, Ghatwai, Nisha, Bayerl, Felix, Xing, Chao, Delk, Nikki A.
Publicado no BMC Cancer (2020)