RELA is sufficient to mediate interleukin-1 repression of androgen receptor expression and activity in an LNCaP disease progression model

BACKGROUND: The androgen receptor (AR) nuclear transcription factor is a therapeutic target for prostate cancer (PCa). Unfortunately, patients can develop resistance to AR-targeted therapies and progress to lethal disease, underscoring the importance of understanding the molecular mechanisms that un...

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Vydáno v:Prostate
Hlavní autoři: Thomas-Jardin, Shayna E., Dahl, Haley, Kanchwala, Mohammed S., Ha, Freedom, Jacob, Joan, Soundharrajan, Reshma, Bautista, Monica, Nawas, Afshan F., Robichaux, Dexter, Mistry, Ragini, Anunobi, Vanessa, Xing, Chao, Delk, Nikki A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000272/
https://ncbi.nlm.nih.gov/pubmed/31730277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23925
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