Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence

Chronic inflammation promotes prostate cancer (PCa) initiation and progression. We previously reported that acute intereluekin-1 (IL-1) exposure represses androgen receptor (AR) accumulation and activity, providing a possible mechanism for IL-1-mediated development of androgen- and AR-independent PC...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dahl, Haley C., Kanchwala, Mohammed, Thomas-Jardin, Shayna E., Sandhu, Amrit, Kanumuri, Preethi, Nawas, Afshan F., Xing, Chao, Lin, Chenchu, Frigo, Daniel E., Delk, Nikki A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743957/
https://ncbi.nlm.nih.gov/pubmed/33326447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242970
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